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Delivery-date: Mon, 09 Nov 2020 07:46:42 -0500
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From: "SelectScience" <product-news@selectscience.com>
To: dr.sultan@jack.ngo
Date: Mon, 09 Nov 2020 12:45:57 +0000 (UTC)
Subject: White Paper: Understanding T Cell phenotype and function to enable better therapeutics
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ont-size: 13px; line-height: 1.2; word-break: break-word; mso-line-height-a=
lt: 16px; mso-ansi-font-size: 14px; margin: 0;"><span style=3D"font-size: 1=
3px; mso-ansi-font-size: 14px;"><strong><span style>White Paper</span></str=
ong></span><span style=3D"font-size: 28px;"><br></span></p></div></div><div style=3D"color:#000000;font-fam=
ily:Arial, Helvetica Neue, Helvetica, sans-serif;line-height:1.2;padding-to=
p:0px;padding-right:20px;padding-bottom:5px;padding-left:20px;"><div style=
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Helvetica Neue, Helvetica, sans-serif; mso-line-height-alt: 14px;"><p style=
=3D"font-size: 28px; line-height: 1.2; word-break: break-word; mso-line-hei=
ght-alt: 34px; margin: 0;"><span style=3D"font-size: 28px;">Understanding T=
 Cell phenotype and function to enable better therapeutics<br></span></p></=
div></div></div></div></div><div class=3D"col num4" style=3D"display: table-cell; vertical-al=
ign: top; max-width: 320px; min-width: 216px; width: 216px;"><div class=3D"=
col_cont" style=3D"width:100% !important;"><div =
style=3D"border-top:0px solid transparent; border-left:0px solid transparen=
t; border-bottom:0px solid transparent; border-right:0px solid transparent;=
 padding-top:5px; padding-bottom:5px; padding-right: 0px; padding-left: 0px=
;"><div class=3D"img-container center fixedwidth" align=3D"=
center" style=3D"padding-right: 0px;padding-left: 0px;"><a href=3D"https://www.selectscience.net/go/?ite=
mID=3D8030&amp;linkID=3Ddownloadpaper&amp;itemTypeID=3D4&amp;mailID=3D13294=
&amp;email=3Ddr.sultan@jack.ngo&amp;URL=3Dhttps%3A%2F%2Fintellicyt.com%2Fwh=
itepaper-understanding-t-cell-phenotype-and-function-to-enable-improved-the=
rapeutics%2F%3Futm_source%3Dselectscience%26utm_medium%3Dextstam%26utm_camp=
aign%3Dimmunology%26utm_term%3DT-Cell-Characterization%26mrksrc%3Dthirdpart=
y%26utm_content%3DWhite-Paper" target=3D"_blank" style=3D"outline:none" tab=
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r Preview" title=3D"Understanding T Cell White Paper Preview" style=3D"text=
-decoration: none; -ms-interpolation-mode: bicubic; height: auto; border: 0=
; width: 100%; max-width: 162px; display: block;" width=3D"162"></a></div></div>=
</div></div></di=
v></div></div><div style=3D"background-color:#f3f3f3;"><div class=3D"block-=
grid " style=3D"min-width: 320px; max-width: 650px; overflow-wrap: break-wo=
rd; word-wrap: break-word; word-break: break-word; Margin: 0 auto; backgrou=
nd-color: #ffffff;"><div style=3D"border-collapse: collapse;display: table;=
width: 100%;background-color:#ffffff;"><div class=3D"col num12" style=3D"mi=
n-width: 320px; max-width: 650px; display: table-cell; vertical-align: top;=
 width: 650px;"><div class=3D"col_cont" style=3D"width:100% !important;"><!=
--[if (!mso)&(!IE)]><div style=3D"color:#000=
000;font-family:Arial, Helvetica Neue, Helvetica, sans-serif;line-height:1.=
2;padding-top:10px;padding-right:20px;padding-bottom:0px;padding-left:20px;=
"><div style=3D"line-height: 1.2; font-size: 12px; color: #000000; font-fam=
ily: Arial, Helvetica Neue, Helvetica, sans-serif; mso-line-height-alt: 14p=
x;"><p style=3D"line-height: 1.2; word-break: break-word; font-size: 18px; =
mso-line-height-alt: 22px; margin: 0;"><span style=3D"font-size: 18px; colo=
r: #000000;">T cells play a vital role in pathogen elimination and tumor im=
munosurveillance. The modulation of T cells is an exciting prospect for the=
 development of novel therapies for immuno-oncology =E2=80=93autoimmune app=
lications, adoptive cell therapy, or vaccine development.<br></span></p></d=
iv></div><div style=3D"color:#=
000000;font-family:Arial, Helvetica Neue, Helvetica, sans-serif;line-height=
:1.2;padding-top:10px;padding-right:20px;padding-bottom:0px;padding-left:20=
px;"><div style=3D"line-height: 1.2; font-size: 12px; color: #000000; font-=
family: Arial, Helvetica Neue, Helvetica, sans-serif; mso-line-height-alt: =
14px;"><p style=3D"line-height: 1.2; word-break: break-word; font-size: 18p=
x; mso-line-height-alt: 22px; margin: 0;"><span style=3D"font-size: 18px; c=
olor: #000000;">In this white paper, we provide an overview of the importan=
ce of understanding T Cell Biology to build better therapeutics. Three case=
 studies demonstrating the use of advanced flow cytometry to study the proc=
esses controlling T cell activation, activity, and exhaustion are described=
.<br></span></p></div></div><d=
iv style=3D"color:#000000;font-family:Arial, Helvetica Neue, Helvetica, san=
s-serif;line-height:1.5;padding-top:0px;padding-right:20px;padding-bottom:5=
px;padding-left:20px;"><div style=3D"line-height: 1.5; font-size: 12px; col=
or: #000000; font-family: Arial, Helvetica Neue, Helvetica, sans-serif; mso=
-line-height-alt: 18px;"><ol><li style=3D"line-height: 1.5; font-size: 18px=
; mso-line-height-alt: 27px;"><span style=3D"font-size: 18px; color: #00000=
0;">Patient to Patient Variability </span></li><li style=3D"line-height: 1.=
5; font-size: 18px; mso-line-height-alt: 27px;"><span style=3D"font-size: 1=
8px; color: #000000;">BiTE antibody evaluation</span></li><li style=3D"line=
-height: 1.5; font-size: 18px; mso-line-height-alt: 27px;"><span style=3D"f=
ont-size: 18px; color: #000000;">CAR-T cell characterization<br></span></li=
></ol></div></div></div></div></div></div></div></div><div style=3D"background-color:#f3f3f3;"><=
div class=3D"block-grid " style=3D"min-width: 320px; max-width: 650px; over=
flow-wrap: break-word; word-wrap: break-word; word-break: break-word; Margi=
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ertical-align: top; width: 650px;"><div class=3D"col_cont" style=3D"width:1=
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